Publications

The effect of age, sex, diet and mood on the immune response

• Robust and prototypical immune responses toward influenza vaccines in the high-risk group of Indigenous Australians by L Hensen, …, KL Flanagan, M Plebanski, … J Davies, SYC Tong and K Kedzierska. PNAS October 12, 2021 118 (41) e2109388118;  https://doi.org/10.1073/pnas.2109388118
• Sex and Gender Differences in the Outcomes of Vaccination over the Life Course by KL Flanagan, AL Fink, M Plebanski and SL Klein. Annu Rev Cell Dev Biol 2017 Oct 6;33:577-599. https://doi.org/10.1146/annurev-cellbio-100616-060718.

Utilising nanoparticles in vaccine development and medicine

• Polymeric Nanoparticles as a Self-Adjuvanting Peptide Vaccine Delivery System: The Role of Shape by P. Koirala, S.-P. R. Chen, J.C. Boer, Z.G. Khalil, C. Deceneux, G. Goodchild, L. Lu, M.O. Faruck, A.O. Shalash, S. Bashiri, R.J. Capon, W.M. Hussein, M.J. Monteiro, M. Plebanski, I. Toth, M. Skwarczynski. Advanced Functional Materials, 2023, https://doi.org/10.1002/adfm.202209304
• Protein Precoating Modulates Biomolecular Coronas and Nanocapsule–Immune Cell Interactions in Human Blood by Li, S.; Ju, Y.; Zhou, J.; Faria, M.; Ang, C.-S.; Mitchell, A.; Zhong, Q.-Z.; Zheng, T.; Kent, S. J.; Caruso, F. J. Mater. Chem. B 2022, 10, 7607-7621.
• Influence of Poly(Ethylene Glycol) Molecular Architecture on Particle Assembly and Ex Vivo Particle–Immune Cell Interactions in Human Blood by Song, J.; Ju, Y.; Amarasena, T. H.; Lin, Z.; Mettu, S.; Zhou, J.; Rahim, M. A.; Ang, C.-S.; Cortez-Jugo, C.; Kent, S. J.; Caruso, F. ACS Nano 2021, 15, 10025-10038.
  
• The Development of Nanoparticles for the Detection and Imaging of Ovarian Cancers by E Henderson, G Huynh, KL Wilson, M Plebanski and S Corrie. Biomedicines 2021, 9(11), 1554; https://doi.org/10.3390/biomedicines9111554
• Person-Specific Biomolecular Coronas Modulate Nanoparticle Interactions with Immune Cells in Human Blood by Y Ju, HG Kelly, LF Dagley, A Reynaldi, TE Schlub, SK Spall, CA Bell, J Cui, AJ Mitchell, Z Lin, AK Wheatley, KJ Thurecht, MP Davenport, AI Webb, F Caruso and SJ Kent. ACS Nano 2020, 14, 11, 15723-15737. https://doi.org/10.1021/acsnano.0c06679
  • This publication attracted media attention and was reported by Herald Sun in Dec 2020: How vaccines could soon be made to order. Herald Sun, 19 Dec 2020. 
    URL: https://www.proquest.com/newspapers/how-vaccines-could-soon-be-made-order/docview/2471292012/se-2?accountid=1237
• Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines by M Skwarczynski, G Zhao, JC Boer, V Ozberk, A Azuar, J Gonzalez Cruz, A Kumar Giddam, ZG Khalil, M Pandey, MA Shibu, WM Hussein, RJ Nevagi, MR Batzloff, JW Wells, RJ Capon, M Plebanski, MF Good and I Toth. Sci Adv. 2020 Jan 29;6(5):eaax2285. eCollection 2020 Jan. DOI: 10.1126/sciadv.aax2285
• A Synthetic Nanoparticle Based Vaccine Approach Targeting MSP4/5 Is Immunogenic and Induces Moderate Protection Against Murine Blood-Stage Malaria by KL Wilson, D Pouniotis, J Hanley, SD Xiang, C Ma, RL Coppel and M Plebanski. Front. Immunol., 15 March 2019 | https://doi.org/10.3389/fimmu.2019.00331
• Therapeutic Cancer Vaccines -T Cell Responses and Epigenetic Modulation by AER Kartikasari, MD Prakash, M Cox, KL Wilson, JC Boer, JA Cauchi and M Plebanski. Front Immunol. 2019 Jan 25; 9:3109. eCollection 2018. https://doi.org/10.3389/fimmu.2018.03109

Improving diagnosis and treatment of ovarian cancer and other cancers

• Mapping Epitopes Recognised by Autoantibodies Shows Potential for the Diagnosis of High-Grade Serous Ovarian Cancer and Monitoring Response to Therapy for This Malignancy by R Moody, K Wilson, N Chandralega Kampan, OM McNally, TW Jobling, A Jaworowski, AN Stephens and M Plebanski. Cancers 2021, 13(16), 4201; https://doi.org/10.3390/cancers13164201
• Tumor-Induced Inflammatory Cytokines and the Emerging Diagnostic Devices for Cancer Detection and Prognosis by AER Kartikasari, CS Huertas, A Mitchell and M Plebanski. Front Oncol 2021 Jul 7; 11:692142. eCollection 2021. Doi:10.3389/fonc.2021.692142
• Potential Impact of Human Cytomegalovirus Infection on Immunity to Ovarian Tumours and Cancer Progression by M Cox, AER Kartikasari, PR Gorry, KL Flanagan, M Plebanski. Biomedicines 2021 Mar 30;9(4):351. https://doi.org/10.3390/biomedicines9040351
• DPP4 Inhibitor Sitagliptin Enhances Lymphocyte Recruitment and Prolongs Survival in a Syngeneic Ovarian Cancer Mouse Model by AL Wilson, LR Moffitt, KL Wilson, M Bilandzic, MD Wright, MD Gorrell, MK Oehler, M Plebanski and AN Stephens. Cancers 2021, 13(3):487; https://doi.org/10.3390/cancers13030487
• Pre-operative sera interleukin-6 in the diagnosis of high-grade serous ovarian cancer by N Chandralega Kampan, M Madondo, J Reynolds, J Hallo, OM McNally, TW Jobling, AN Stephens, MA Quin and M Plebanski. Sci Rep. 2020 Feb 10;10(1):2213. https://doi.org/10.1038/s41598-020-59009-z.
  • This publication led to Magdalena’s role as the spokesperson for the Ovarian Cancer Research Foundation (OCRF) State of the Nation Report: live online launch Aug 2020, and interviews on television (channel 10) and in print media locally (Herald Sun) and around the world (see below), https://www.facebook.com/OCRFaustralia/videos/watch-state-of-the-nation-in-ovarian-cancer-research-audit-report-launch/329463138250230/
  • ‘Simple blood test developed to improve ovarian cancer diagnosis’, The Siasat Daily Newspaper (India), 18th February 2020, https://www.siasat.com/simple-blood-test-developed-improve-ovarian-cancer-diagnosis-1828655/
  • ‘Simple blood test can improve ovarian cancer diagnosis’ Hudson Research Institute, 11th March 2020, https://hudson.org.au/latest-news/simple-blood-test-can-improve-ovarian-cancer-diagnosis/
• Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects by R Daillère, M Vétizou, N Waldschmitt,…, M Plebanski, M Madondo, ..., I Gomperts Boneca, M Chamaillard and L Zitvogel. Immunity, Volume 45, Issue 4, 18 October 2016, Pages 714-716. https://doi.org/10.1016/j.immuni.2016.09.009

Understanding COVID-19 and improving vaccine response

• Anti-Peg Antibodies Boosted in Humans by SARS-CoV-2 Lipid Nanoparticle mRNA Vaccine by Ju, Y.; Lee, W. S.; Pilkington, E. H.; Kelly, H. G.; Li, S.; Selva, K. J.; Wragg, K. M.; Subbarao, K.; Nguyen, T. H. O.; Rowntree, L. C.; Allen, L. F.; Bond, K.; Williamson, D. A.; Truong, N. P.; Plebanski, M.; Kedzierska, K.; Mahanty, S.; Chung, A. W.; Caruso, F.; Wheatley, A. K.; Juno, J. A.; Kent, S. J. ACS Nano 2022, 16, 11769-11780.
• Impact of Anti-PEG Antibodies Induced by SARS-CoV-2 mRNA Vaccines by Ju, Y.; Carreño, J. M.; Simon V.; Dawson K.; Krammer F.; Kent, S. J. Nat. Rev. Immunol. 2022, in press.
  
• Predicted B Cell Epitopes Highlight the Potential for COVID-19 to Drive Self-Reactive Immunity by R Moody, KL Wilson, JC Boer, JK Holien, KL Flanagan, A Jaworowski and M Plebanski. Front. Bioinform., 19 August 2021 | https://doi.org/10.3389/fbinf.2021.709533