STAFF PROFILE
Dr. Jessica Holien
Position:
Senior Lecturer, Computational Biology
College / Portfolio:
STEM College
School / Department:
STEM|School of Science
Phone:
+61399257256
Email:
jessica.holien@rmit.edu.au
Campus:
Bundoora West
Contact me about:
Research supervision
- Williams, N.,Rodrigues, C.,Truong, J.,Ascher, D.,Holien, J. (2023). DockNet: high-throughput protein-protein interface contact prediction In: Bioinformatics (Oxford, England), 39, 1 - 3
- Massudi, H.,Luo, J.,Holien, J.,Gadde, S.,Marsh, G. M., et al, . (2023). Inhibitors of the Oncogenic PA2G4-MYCN Protein-Protein Interface In: Cancers, 15, 1 - 22
- Nguyen, D.,Holien, J.,Dekiwadia, C.,Thrimawithana, T.,Piva, T.,Huynh, T. (2023). Momordica cochinchinensis (G?c) Seed Extracts Induce Apoptosis and Necrosis in Melanoma Cells In: Pharmaceuticals, 16, 1 - 21
- Holien, J.,Coff, L.,Guy, A.,Boer, J. (2023). Drug Discovery in Real Life: An Online Learning Activity for Bioinformatics Students In: Journal of Chemical Education, 100, 1053 - 1057
- Gadde, S.,Kleynhans, A.,Holien, J.,Bhadbhade, M., et al, . (2023). Pyrimido[1,2-a]benzimidazoles as inhibitors of oncoproteins ubiquitin specific protease 5 and MYCN in the childhood cancer neuroblastoma In: Bioorganic Chemistry, 136, 1 - 17
- Nelson, N.,Feurstein, S.,Niaz, A.,et al, .,Holien, J. (2023). Functional genomics for curation of variants in telomere biology disorder associated genes: A systematic review In: Genetics in Medicine, 25, 1 - 1
- Cody, V.,Truong, J.,Holdsworth, B.,Holien, J.,Richardson, S.,Chalmers, D.,Craik, D. (2022). Structural Analysis of the Complex of Human Transthyretin with 3',5'-Dichlorophenylanthranilic Acid at 1.5 Å Resolution In: Molecules, 27, 1 - 11
- Boer, J.,Pan, Q.,Holien, J.,Nguyen, T.,Ascher, D.,Plebanski, M. (2022). A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility In: Frontiers in Immunology, 13, 1 - 13
- Rosdah, A.,Abbott, B.,Langendorf, C.,Deng, Y.,Truong, J.,Holien, J., et al, . (2022). A novel small molecule inhibitor of human Drp1 In: Scientific Reports, 12, 1 - 13
- Deng, Y.,Ngo, D.,Holien, J.,Lees, J.,Lim, S. (2022). Mitochondrial Dynamin-Related Protein Drp1: a New Player in Cardio-oncology In: Current Oncology Reports, 24, 1751 - 1763
- Targeting HOXA1-expressing stem cells to improve therapies for myelodysplastic syndromes (Administered by St Vincent’s Institute of Medical Research). Funded by: NHMRC-Ideas Grants from (2022 to 2025)
- Reducing tumour incidence in adolescents with germ-line mutations in RECQL4 (Administered by St Vincent’s Institute of Medical Research). Funded by: MRFF - 2021 Childhood Cancer Research from (2021 to 2024)
- Testing therapies in mucinous ovarian cancer in novel patient-derived models (Administered by The University of Melbourne). Funded by: US Army Medical Research and Material Command - Competitive Funding 2021 from (2021 to 2023)
- Identification of a molecule to enhance myelin repair. Funded by: CASS Foundation - grant from (2021 to 2023)
- Career recovery grants: Jessica Holien. Funded by: Veski - Inspiring Women Career Recovery Grants from (2021 to 2022)
7 PhD Current Supervisions and 2 Masters by Research Current Supervisions