Stella Liong

Dr. Stella Liong

Research Fellow (Postdoctoral)

Details

  • College: School of Health and Biomedical Sciences
  • Department: Health and Biomedical Sciences
  • Campus: Bundoora West Australia
  • stella.liong@rmit.edu.au

Open to

  • Masters Research or PhD student supervision

About

Dr Liong is a mid-career postdoctoral research fellow (PhD 2013 with two career disruptions) with research expertise in respiratory viral infections, cardiovascular disease, immunology, and reproductive sciences. In 2018, she was awarded the prestigious RMIT Vice-Chancellor Postdoctoral Research Fellowship. Her research interests are on respiratory viral infections such as influenza virus and respiratory syncytial virus (RSV) and how these viruses cause respiratory, cardiovascular and neurological complications in vulnerable populations using preclinical models. She also has an extensive research background investigating polyphenols, which have potent antioxidant and anti-inflammatory properties, and their effects on pregnancy complications using clinical samples and preclinical models.

 

Her research has identified a new understanding on the pathophysiology of influenza infection during pregnancy and how it leads to both maternal and foetal complications. Her research has shown that immunity during pregnancy is not suppressed but rather can become overactivated by viral infections resulting in severe systemic inflammation which is a major driver of maternal and foetal complications. She has identified that influenza infection in pregnancy causes maternal cardiovascular dysfunction comprising of vascular inflammation and endothelial dysfunction which leads to impaired blood flow to the placenta and foetal growth restriction.

 

She has received $2.93M in research support, including an NHMRC Ideas Grant as CIB on influenza and pregnancy compliations ($1.3M). She has also received fellowship support from University of Melbourne (Early Career Researcher Grant), the Royal Australian and New Zealand College of Obstetrics and Gynaecology (Glyn White Fellowship), Australian Endocrinology Society (ESA Postdoctoral Award) and the Harold Mitchell Foundation (Postdoctoral Travel Fellowship).

 

 

 

Invited talks: Australian Influenza Symposium, The Peter Doherty Institute for Infection and Immunity (2021); The GOSS seminar series, Department of Obstetrics & Gynaecology, The University of Melbourne (2022); keynote speaker at the ASCEPT joint Drug Discovery and Respiratory & Inflammation SIG virtual symposium (2020); Visiting Researcher Seminar Series, UniSA (2023); International Federation of Placenta Associations workshop IV (2015)

 

Podcasts: Got Guts podcast series, American Journal of Physiology-Gastrointestinal and Liver Physiology.

 

Awards: Rising Stars Award, CHA Medical Research Symposium (best oral award, 2016); Emerging Investigator Award, Australasian Diabetes in Pregnancy Society (ADIPS) (best oral award, 2015); SRI-Pardi President's Distinguished Scientist Award, 62nd Annual Meeting Society of Reproductive Investigation (2015).

Supervisor projects

  • The viral origins of cardiovascular disease in women
  • 20 May 2024
  • Dysregulated Immune Responses via Toll-Like Receptor 7 Drive Maternal and Fetal Disease Pathogenesis During Gestational Influenza A Virus Infection
  • 16 Mar 2022
  • The Cardiovascular Consequences of Influenza A Virus Infection: Mechanisms and Therapies for High-risk Groups
  • 23 Jan 2020
  • Maternal and Fetal Complications During Influenza A Virus Infection
  • 4 Jun 2018

Teaching interests

Research keywords:

Pregnancy, Respiratory Viruses, Cardiovascular Disease, Respiratory Disease, Neurodevelopmental Disorders, Immunology

 

Supervisor interest areas:

Respiratory viruses

Pregnancy research

Neurodevelopment

Cardiovascular disease

 

Supervisor projects:

Influenza virus induced complications in pregnancy
Maternal and Fetal Complications During Influenza A Virus Infection
Investigating novel therapeutics for respiratory infectious diseases during pregnancy

 

Programs (https://www.rmit.edu.au/study-with-us/science/medical-sciences):

BIOL2565 Cellular Pathways

Research interests

Dr Stella Liong's research is focused on understanding how respiratory viral infections drive severe disease in at risk populations who are pregnant or have pre-exisiting cardiovascular disease. One key area of interest is how respiratory viral infections cause systemic disease in at-risk popualations. Influenza infection during pregnancy is associated with severe vascular inflammation and dysfunction. This maternal vascular dysfunction during influenza infection can have long-lasting detrimental effects on foetal neurodevelopment.

 

Dr Liong's other area of research is focused on the viral origins of neurodevelopmental diseases, in particular schizophrenia disorder. Influenza during pregnancy can induce behavioural deficits in the adult offspring and her work aims to understand how maternal viral infections can predispose the offspring to neurodevelopmental disorders later in life. 

 

Research keywords:

Pregnancy, Respiratory Viruses, Cardiovascular Disease, Respiratory Disease, Neurodevelopmental Disorders, Immunology

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Acknowledgement of Country

RMIT University acknowledges the people of the Woi wurrung and Boon wurrung language groups of the eastern Kulin Nation on whose unceded lands we conduct the business of the University. RMIT University respectfully acknowledges their Ancestors and Elders, past and present. RMIT also acknowledges the Traditional Custodians and their Ancestors of the lands and waters across Australia where we conduct our business - Artwork 'Sentient' by Hollie Johnson, Gunaikurnai and Monero Ngarigo.